Nutrition Supplements
& Customised Nutrition Services
Our Supplements
At UKRC our nutrition supplements have you covered. No matter what your needs are we put quality and science into every product we produce.
United Kingdom Rejuvenation Centre (UKRC) only operates with State of the Art and certified manufacturing facilities. Working with our contract manufacturing factories ensures that the formations, quality and manufacturing facilities are second to none.
This ensures that all supplements and formulations:
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Follow all regulatory standards
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We work with qualified and industry recognised Nutritionists to ensure all our formulations meet with the requirements and quality of UKRC products
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Our facility is FDA registered, GMP compliant and ISO 22000 certified and where required we have a organic certified manufacturing facility
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Our manufacturing facility can manufacture organic certified products
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We have close controls on our factory manufacturing processes
Our Supplement Services
At UKRC we offer two options for our supplements service. All our supplements can be shipped globally and all are produced in our UK manufacturing facility.
Customised Supplements
Personalised supplements. Made specifically for you through our team of qualified and accredited consultant nutritionists. Ensuring your needs and requirements are met at every stage of your nutrition requirements
Traditional Supplements
Quality manufactured supplements. Made with high quality ingredients and made to deliver quality, essentials and nutrition for your body and lifestyle.
Applying science from our team of qualified and accredited consultant nutritionists.
Why UKRC Supplements?
Customisations
Our team of nutritionists and panel of health and wellbeing professionals have developed a complex and algorithm to identify the needs of the patient.
This means that though answering questions about health, lifestyle and goals we are able to tailor your nutrition requirements and deliver to you supplements specifically for your needs
Developed by Nutritionists
Our supplements are developed by our team of qualified nutritionists and experts in health, body, wellbeing and mind.
This allows us to ensure that both our personalised supplements and standard supplement ranges deliver the very best for you or your clients
Manufactured in Britain
All our Supplements are Made in Britain.
This ensures that our products meet the highest quality standards and to strict GMP, ISO and QMS standards.
All our ingredients are checked and rechecked by a team of lab technicians to ensure the grade and quality of our ingredients matches out nutritionists requirements always
Shipping Globally
We ship globally.
Our factories are used to shipping globally and through out network of trusted carriers we are able to ensure that products are shipped quickly and effectively to their end destination
Low Lead Times
Our lead times are around 4-6 weeks.
Our factory state of the art equipment allows us to manufacture great quality supplements, accurately and quickly
Customised Supplements
We have designed a nutrition personalised quiz with our team of qualified nutritionists.
Together with the formulas and recommendations that sit in the background, they've taken the latest research into account to ensure that we deliver exactly what you or your client needs.
Our personalised quiz can be re-programmed based on your business and customer needs in order to identify the right nutritional products based on quiz answers.
From weight loss, improving your hair, skin or nails or simply to give your body a boost, our quiz can take all of these areas and more into account and recommend suitable combinations of supplements to support you or your clients needs and lead to a healthier and nutrient filled lifestyle.
How does it work?
We focus on 3 areas with multiple questions and adapt depending on the answers
Diet
Lifestyle
Goals
Our complex algorithm will then look at the answers and recommend a personalised supplement routine. It really is that simple!
Superior Quality and Standards
Our Supplements are manufactured to the highest standards possible and are all made in Britain.
We believe in our supplements, their nutritional values and benefits and at UKRC we ensure that our supplements pass not only their regulatory checks but also our taste tests!
Our processes are strict but in a nutshell:
Step 2 - Selection of Raw Materials
A well-formulated dietary supplement requires the use of evidence-based ingredients to help assure product efficacy. Ingredients may be selected worldwide on the basis of quality, and eying forms that provide high potency and bio-availability. For example, many mineral supplements include well-absorbed mineral salts bonded to organic acids, including citrates, picolinates, and gluconates. Likewise, formulas with herbal extracts may include standardized extracts with guaranteed amounts of the natural active or marker compound within the herbs.
Timeline:
The formulation of the product and the selection of raw materials are part of the same process. The timeline for this differs greatly from product to product. It may take as little as a week, or as much as a few years. In any case, we really don’t count the original formulation and raw material selection as part of the production process.
Our raw materials only come from sources who also follow our practices and comply with the legal requirements for food manufacturing and supply in the United Kingdom. This ensures that only the best ingredients are used in our supplement formulations.
Step 3 - Ordering our Raw Materials
Depending on the formulation we will either stock or need to order further ingredients for our supplements.
Without question, this is the step that takes the longest in the manufacturing process.
Why? Here’s an example.
Let’s say that the raw material in question is a probiotic. As live microorganisms, probiotic ingredients are typically made to order. They literally must be grown on a natural medium, and that doesn’t happen overnight. In fact, growing probiotics may take 6 weeks or so. Now let’s say those probiotics come from Italy (which is often the case), so that means the finished material will be shipped internationally - which will take 1-2 weeks.
Of course, there are many raw materials other than probiotics - some of which have better stability and may even be stocked on our manufacturing facility. This will take 2-4 weeks to arrive.
Step 4 - Raw Materials Arrive, are Quarantined & Tested
Once the raw materials arrive at the factory, GMP regulations require that they be quarantined and tested before they are released into inventory. This is also a process we follow for our ISO 22000 and ISO9001 processes. The type of testing required includes identity and potency, microbiological compliance, and heavy metal compliance.
Identity and potency:
To test for identity and potency, there must be an established methodology for testing the raw material ingredient. That methodology may exist in the Pharmacopeia, or by provided by some other credible source. Not only must that methodology be followed, but a standard will need to be purchased if our factory doesn’t already have the standard. If you didn’t already know, a standard is a validated sample of the raw material ingredient that our laboratory will use for comparison purposes. The raw material will be tested against the standard using appropriate laboratory equipment to see if it matches. Appropriate lab equipment may include Fourier Transform Infrared (FT-IR) Spectroscopy, Ultra Violet-visible (UV-VIS) Spectroscopy, Inductively Coupled Plasma - Mass Spectrometry (ICP-MS), and High-Performance Liquid Chromatography (HPLC). In this way, identity and potency can be established.
Microbiological testing:
Next, the raw material must be tested for microbiological compliance to verify that it does not contain dangerous levels of microorganisms such as E. coli. Special equipment in a separate microbiological laboratory will be required for this purpose. Whilst we do have an in-house testing lab, the raw material will also be sent to a third-party lab for micro testing.
Heavy metal testing:
Finally, heavy metal testing for lead, mercury, cadmium and arsenic must also be conducted. Not only is this required and the right thing to do anyway, but California Prop 65 requirements are associated with some hefty fines if your product fails to meet their more stringent heavy metal requirements.
Once the raw materials have passed testing they will be released into inventory and placed into their registered holding area based on their storage requirements. All inventory items are fully electronically logged, batch referenced and location referenced to ensure full traceability of all ingredients.
Step 5 - R&D Batch
Once all of the raw materials have been released into inventory, an R&D batch is created. This is where the raw materials will all be mixed together, and a limited number of tablets and capsules will be produced in the lab to ascertain that the formulation will work in a finished dosage form. Depending upon the situation, these are then checked and evaluated and only once they have been approved will the factory move onto the pilot batch.
Step 6 - Pilot Batch
Using our learning from the R&D batch we will next run a pilot batch of the product on the actual production equipment. This is necessary to determine that the product will run correctly on the equipment during the actual production run. If there are any issues, the formulation may need to be adjusted. If everything goes well, the factory will then move onto the full production run.
Step 7 - Production Run and Testing
The production run is when the finished product will be produced. There are several steps in the process, including some additional testing that needs to be done. This includes uniformity of mix, content uniformity, dissolution testing, and a repeat of the tests done on the raw materials (identity and potency, microbiological compliance, and heavy metal compliance).
Uniformity of mix:
All of the raw materials which comprise a given dietary supplement are mixed together in a large-scale commercial mixer. During this process, it is vital that the raw materials are completely and uniformly mixed to assure that there is an even distribution of each specified vitamin, mineral, herb, etc. (“nutrients”) throughout the entire batch. A uniform mix is important since we want all the capsules, tablets, powders or liquids which will be made from a batch of raw materials to consistently have the proper, predetermined amount of nutrients in them. A sample of the mixed blend is taken to the lab, and the levels of certain ingredients are tested to verify that the mix is indeed uniform.
Content uniformity (spot testing tablet weight):
After determining that the mix is uniform, the next step is to ensure that each tablet and capsule has the correct weight in order to verify its nutrient potency. This is known as “content uniformity.” While capsules are being filled or tablets are being punched during the manufacturing process, their weight is regularly spot tested. In addition, to capturing weight uniformity data, additional data regarding thickness and hardness is also recorded. For both capsules and tablets, content uniformity is charted to ensure results within the specified range. If for any reason, there is an unacceptable variation from the product specifications for content uniformity (weight, thickness, density), those capsules or tablets are rejected.
Dissolution testing:
Dissolution testing is a process whereby the capsule or tablet falls is put into temperature-controlled water and then agitated (moved around in a small container) to similar the muscular action of digestion. If the tablets/capsules dissolve within 45 minutes in water, it is reasonable to believe that it will likewise dissolve in the human digestive tract, and its component nutrients will be ready for absorption.
Stability testing:
If expiration dates appear on the label of a product, then stability testing must be conducted. Stability testing helps identify which nutrients are most vulnerable to damage and to what degree potency is affected. By accounting for such variables as specific ingredients, dosage form, packaging and storage conditions, it can determine how much of an increase in the potency for a given nutrient is needed to compensate for potency losses over time. There are two types of stability testing: 1) accelerated stability, and 2) ambient stability.
i. Accelerated stability:
During accelerated stability, a dietary supplement in its intended packaging is placed inside an environmental chamber that controls temperature and humidity. This chamber will create conditions that are designed to accelerate the normal aging of a product. For example, if a product spends one month in the accelerated machine, it may be the approximate equivalent of six months aging time. When the product is removed, we can then test it for potency loss and other effects.
ii. Ambient stability:
Ambient stability is determined by taking a sample of the packaged product we manufacture and holding it in a retain room under controlled, ambient temperature and humidity. The retain room is used to correlate and confirm shelf life results from accelerated testing. At regular intervals, during its shelf life, a product is pulled from the retain room and tested for potency which is then compared to the accelerated aging studies.
Step 8 - Testing of Finished Products
Once the finished tablets from the production batch have been made, a repeat for the same types of tests done on the raw materials is performed, including identity and potency, microbiological compliance, and heavy metal compliance. The factory will then produce a certificate of analysis (COA) which will be logged and stored against the completed batch.
After completion of each finished batch the production machine will be thoroughly cleaned and prepared for the next product to be manufactured. This can take anywhere between 2-12 hours depending on the machine used. Machine cleaning processes are documented and records stored for future use and logged against each manufacturing batch number.
Step 9 - Packaging
The finished tablets will now move onto the packaging line.
Here the following is completed:
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The machinery is visually checked to ensure that it is in full working order
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A sanitisation process is completed as a sense check for the machine
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A test package is set up and a series of packaging profile checks are completed and logged
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The machine is loaded with the bottles, caps/ materials to be used for the machine
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All labels and product information relating to the bottle/ package are loaded and verified both electronically and also via checks with no fewer than 2 production colleagues
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The machine is loaded with the tablets/ finished product and the packaging process is started
During this process checks are made both electronically by the packaging line machines and also by colleagues who will check and log the details of the batches and bottles being checked and packaged.
All products are placed into their relevant packaging boxes and are labelled to include their run and production references.
Step 10 - Storage and Shipping
Products are stored in dry and clean storage areas which have been designed specifically for the storage of the finished product.
Products are electronically logged with their storage location.
Once ready to dispatch the products will be logged and registered against their shipping box / location. This is completed via the picking and packing process and electronically stored in the product production stock system.
This ensures full traceability and identification of all products produced.